7 Important Signs of Leukemia You Shouldn’t Ignore

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Leukemia is a blood cancer, and blood cancers account for about 10% of all new cancer diagnoses each year. Leukemia is also the most common cancer occurring in children and teens, representing about 1 in 3 new cases each year.

And while 5-year survival rates have gone up significantly since 1960, now sitting at about 63.7%, it is still critically important to be aware of the signs and symptoms that indicate the possibility of leukemia.

Like many cancers, leukemia is generally asymptomatic in its early stages. But because blood flows all over your body, blood cancers are prone to spreading quickly. That’s why it is so important to be tuned into your body and to teach your children to communicate about how they’re feeling.

Awareness is one of the best ways to protect your health and that of your family. Stay with us as we describe 7 important signs of leukemia that you cannot afford to ignore. Symptom #5 might strike you as a good thing at first, but is very dangerous in conjunction with some of the other signs. To understand a bit more about what leukemia actually is, we’ll finish up with descriptions of the 4 most common types.

1. Symptoms of Leukemia

Anemia and Related Symptoms

Though many types of leukemia aren’t necessarily symptomatic in early stages. It is important to track your overall health to determine whether one or more of these symptoms has popped up in recent months.

Anemia is a condition in which your blood lacks enough healthy red blood cells to carry oxygen throughout the body. As a result, your cells may begin to starve. Symptoms of anemia include fatigue, pale skin, and feeling fluish.

2. Bleeding or Bruising Easily

As a blood cancer, leukemia can affect how much or how easily you bleed. If you find that the smallest bump leaves you bruised or caused tiny spots of blood to appear under the skin, that’s a warning sign.

Leukemia might also cause blood to appear in urine or stool, increase the frequency of nosebleeds, or make your gums bleed while eating or brushing.

3. Susceptibility to Infections

If you were previously able to avoid many seasonal bugs but are now sick more often that you’re healthy, leukemia could be at fault.

It most commonly causes sore throat or bronchial pneumonia, including symptoms like low-grade fever, headache, mouth sores, or skin rash, but any old bug takes hold more easily in a body with cancer.

4. Swollen Lymph Nodes

When caused by leukemia, swollen lymph nodes usually occur in the throat, armpits, or groin. However, lymph nodes also swell in response to common infections and even stress. Alone, swollen lymph nodes do not point directly to leukemia. Track this symptom if you are experiencing any others on our list as well.

5. Loss of appetite and weight

leukemia doesn’t attack your digestive system directly, the associated cancer cells do produce substances that are known to change the way a body metabolizes food.

These toxins may cause a chronic lack of appetite that leads to unintended weight loss.

6. Pain Under the Left Lower Ribs

Some forms of blood cancer irritate and enlarge the spleen, causing painful pressure under the ribs on the lower left side. An enlarged spleen may also press on your stomach, making you feel full even when you haven’t eaten, and contributing to the loss of appetite we mentioned earlier.

7. Night sweats

Night sweats happen when your body temperature rises overnight and sweating is triggered to try and cool it down. You may not notice getting too hot, but you will likely wake up when you become chilled due to drenched pajamas.

There are many causes of night sweats, but in terms of leukemia, they may be triggered by infection or sudden fever.

Types and Classifications of Leukemia

Leukemia is described based on the type of white blood cells that it attacks. Lymphocytic leukemia occurs in certain white blood cells called lymphocytes within the bone marrow. Myeloid leukemia tends to start in other white blood cells rather than the lymphocytes, and can show up in red blood cells and platelets as well.

Leukemia is also described based on how aggressively the cancer grows. When it comes out of nowhere and grows very quickly, it is described as acute. But if the cells grow and multiply slowly yet consistently, the cancer is described as chronic.

Following are the four most commonly diagnosed types of leukemia.

Acute Myeloid Leukemia (AML)

AML is the most common form of acute leukemia. It happens when bone marrow makes something called “blasts,” which are basically immature cells. In healthy bone marrow, blasts go on to develop into white blood cells. But with AML, the cells do not mature and are unable to fight off infections.

At the same time, the bone marrow often starts pumping out cancerous red blood cells and platelets, which increase rapidly and begin to overtake the space needed for healthy red blood cells and platelets to function properly.

Acute Lymphocytic Leukemia (ALL)

With ALL, abnormal white blood cells accumulate in bone marrow and replace the healthy cells necessary to produce functioning lymphocytes with cancerous cells that cannot mature properly.

These abnormal cells are carried throughout the body in the bloodstream, which makes them prone to infecting other organs like the brain, lymph nodes, liver, and testes. This form of leukemia can happen at any age, but is found most commonly in people under 15 or over 45 years.

Chronic Lymphocytic Leukemia (CLL)

CLL is a slower-growing form of leukemia that may be in progress for several years before it becomes noticeable.

It begins in the lymphocytes in bone marrow and will eventually crowd out normal blood cells; this in turn makes it difficult for the body to fight infections. CLL can spread to the lymph nodes and from there to organs including the spleen and liver.

Chronic Myeloid Leukemia (CML)

CML is a chronic or slow-growing leukemia, at least at first. It begins in the bone marrow with abnormalities of blood-forming cells, and over time, these cancerous cells make their way into the bloodstream and around the body. But while CML might start slowly, it can shift into an acute form that may affect any organ.

CML is also different in that it has a known association with an abnormal chromosome called the Philadelphia chromosome. CML diagnoses account for 10-15% of all types of leukemia and tends to strike older people. The average age for a first diagnosis is 67 years old.


The leukemia signs we have described are early symptoms and are relatively mild, but more advanced leukemia with a very high white blood cell count can cause vision problems, ringing in the ears, stroke, or significant changes in mental status.

Please get in to see your doctor as quickly as possible if you identify a pattern of the symptoms we have described. Don’t panic, as there are many potential causes for these issues, but remember that your best chance of successful treatment comes with early detection.

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